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Estero to Jacksonville buses

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Trip Overview

The average bus between Estero and Jacksonville takes 15h 9m and the fastest bus takes 14h 53m. The bus service runs several times per day from Estero to Jacksonville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 9m
Duration
376 mi
Distance
$73
Average price
Twice daily
Frequency

Estero to Jacksonville bus times

Buses run twice daily between Estero and Jacksonville. The earliest departure is at 10:04 AM in the morning, and the last departure from Estero is at 4:35 PM which arrives into Jacksonville at 7:45 AM. All services require a transfer at South Fort Myers Transfer/P&R and take an average of 15h 9m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA14h 53m • 3 changes
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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA15h 9m • 3 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA14h 53m • 3 changes
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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA15h 9m • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA14h 53m • 3 changes
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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA15h 9m • 3 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA14h 53m • 3 changes
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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA15h 9m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA15h 20m • 3 changes
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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA15h 10m • 3 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA14h 53m • 3 changes
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    Arrives next day

    Lee County TransitLee County TransitFlixbus USAFlixbus USA16h 14m • 3 changes

Frequently asked questions

Want to know about travelling from Estero to Jacksonville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Estero to Jacksonville.ExpandLaunch map view
  • Distance: 376.2 mi
  • Duration: 15h 9m

What companies run services between Estero, FL, USA and Jacksonville, FL, USA?

You can take a bus from S Tamiami Trl @ Lords Way St to Jacksonville via South Fort Myers Transfer/P&R, Fort Myers Bus Stop, and Orlando Bus Station in around 10h 42m.

Operators