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Estero to Myrtle Beach buses

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Trip Overview

The average bus between Estero and Myrtle Beach takes 43h 40m and the fastest bus takes 43h 1m. The bus runs, on average, 3 times per week from Estero to Myrtle Beach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

43h 40m
Duration
931 mi
Distance
$176
Average price
3 times a week
Frequency

Estero to Myrtle Beach bus times

Buses run 3 times a week between Estero and Myrtle Beach. The earliest departure is at 4:33 PM in the afternoon, and the last departure from Estero is at 4:34 PM which arrives into Myrtle Beach at 11:35 AM. All services require a transfer at South Fort Myers Transfer/P&R and take an average of 43h 40m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    Arrives +2 days

    Lee County TransitLee County TransitFlixbus USAFlixbus USAGreyhound USA44h • 4 changes

Departing Saturday, October 31, 2026

  •  → 

    Arrives +2 days

    Lee County TransitLee County TransitFlixbus USAFlixbus USAGreyhound USA44h • 4 changes

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    Lee County TransitLee County TransitFlixbus USAFlixbus USAGreyhound USA43h 1m • 4 changes

Frequently asked questions

Want to know about travelling from Estero to Myrtle Beach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Estero to Myrtle Beach.ExpandLaunch map view
  • Distance: 931.4 mi
  • Duration: 43h 40m

What companies run services between Estero, FL, USA and Myrtle Beach, SC, USA?

You can take a bus from S Tamiami Trl @ County Rd to Myrtle Beach Bus Station via South Fort Myers Transfer/P&R, Fort Myers Bus Stop, Orlando Bus Station, and Fayetteville Bus Station in around 22h 48m.

Operators