The average bus between Firenze Santa Maria Novella and Genova Brignole takes 4h 33m and the fastest bus takes 3h 38m. The bus service runs several times per day from Firenze Santa Maria Novella to Genova Brignole. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Firenze Santa Maria Novella and Genova Brignole. The earliest departure is at 3:05 AM at night, and the last departure from Firenze Santa Maria Novella is at 11:05 PM which arrives into Genova Brignole at 2:43 AM. All services require a transfer at Statuto and take an average of 4h 33m. The schedules shown below are for the next available departures.

5h 55m • 1 change
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8h 15m • 1 change
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3h 38m • 1 change

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3h 38m • 1 change

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3h 38m • 1 change

5h 55m • 1 change
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8h 15m • 1 change
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3h 38m • 1 change

5h 55m • 1 change
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8h 15m • 1 change
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3h 38m • 1 change
Want to know about travelling from Firenze Santa Maria Novella to Genova Brignole? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Firenze Santa Maria Novella to Genova Brignole. However, there are services departing from Firenze Santa Maria Novella station and arriving at Genova Brignole station via Genoa - Via Fanti d'Italia Bus Stop. The journey, including transfers, takes approximately 4h 33m.
Firenze Santa Maria Novella to Genova Brignole bus services, operated by FlixBus, depart from Florence - Villa Costanza station.
Firenze Santa Maria Novella to Genova Brignole bus services, operated by FlixBus, arrive at Genoa - Via Fanti d'Italia Bus Stop station.
Book your Firenze Santa Maria Novella to Genova Brignole bus tickets online with FlixBus and AMT Genova.
The distance between Firenze Santa Maria Novella and Genova Brignole is 196 km. The road distance is 244 km.
Itabus S.p.A. operates a bus from Florence - Villa Costanza to Genoa - Via Fanti d'Italia Bus Stop 4 times a week. Tickets cost €14–30 and the journey takes 2h 45m.