The average bus between Florence and Acquasanta Terme takes 6h 43m and the fastest bus takes 6h 15m. The bus service runs several times per day from Florence to Acquasanta Terme. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Florence and Acquasanta Terme. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 1:05 PM which arrives into Acquasanta Terme at 7:50 PM. All services require a transfer, and take on average 6h 43m. The schedules shown below are for the next available departures.

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Want to know about travelling from Florence to Acquasanta Terme? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Acquasanta Terme. However, there are services departing from Florence station and arriving at Acquasanta Terme station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 6h 43m.
Florence to Acquasanta Terme bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Acquasanta Terme bus services, operated by FlixBus, arrive at Acquasanta Terme station.
The distance between Florence and Acquasanta Terme is 208 km. The road distance is 449 km.
You can take a bus from Florence Villa Constanza Bus Station to Acquasanta Terme via Roma, Autostazione Tiburtina in around 7h 5m.