The average bus between Florence and Agnone takes 10h 28m and the fastest bus takes 7h 35m. The bus service runs several times per day from Florence to Agnone. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Florence and Agnone. The earliest departure is at 6:10 AM in the morning, and the last departure from Florence is at 5:05 PM which arrives into Agnone at 7:50 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 10h 28m. The schedules shown below are for the next available departures.


8h 50m • 2 changes


7h 35m • 2 changes
Arrives next day


17h 40m • 2 changes


8h 50m • 2 changes


7h 35m • 2 changes


8h 30m • 2 changes
Arrives next day


17h 40m • 2 changes
Want to know about travelling from Florence to Agnone? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Agnone. However, there are services departing from Florence station and arriving at Agnone station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 10h 28m.
Florence to Agnone bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Agnone bus services, operated by FlixBus, arrive at Agnone station.
The distance between Florence and Agnone is 336.4 km. The road distance is 493 km.
You can take a bus from Florence Villa Constanza Bus Station to Agnone via Roma, Autostazione Tiburtina and Isernia in around 8h 15m.