Florence to Brindisi Buses

Florence to Brindisi buses

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Trip Overview

The average bus between Florence and Brindisi takes 12h 17m and the fastest bus takes 11h 30m. The bus service runs several times per day from Florence to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 17m
Duration: 814 km
Distance: €80
Average price: 5 times a day
Frequency

Bus via Rome

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...
Take the bus from Roma, Autostazione Tiburtina to Brindisibus 573 / ...

11h 40m

€59–106

Florence to Brindisi bus times

Buses run 5 times a day between Florence and Brindisi. The earliest departure is at 3:35 AM at night, and the last departure from Florence is at 7:45 PM which arrives into Brindisi at 7:15 AM. All services require a transfer, and take on average 12h 17m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

6:00 AM → 6:25 PM
12h 25m • 1 change
6:30 PM → 6:10 AM
Arrives next day
11h 40m • 1 change
7:45 PM → 7:15 AM
Arrives next day
11h 30m • 1 change

Departing Saturday, November 7, 2026

3:50 AM → 4:40 PM
12h 50m • 1 change
4:40 AM → 5:34 PM
12h 54m • 1 change
6:10 AM → 6:25 PM
12h 15m • 1 change
6:30 PM → 6:10 AM
Arrives next day
11h 40m • 1 change
Show more

Departing Sunday, November 8, 2026

3:50 AM → 4:40 PM
12h 50m • 1 change
4:40 AM → 5:34 PM
12h 54m • 1 change
6:10 AM → 6:25 PM
12h 15m • 1 change
6:30 PM → 6:10 AM
Arrives next day
11h 40m • 1 change
Show more

Departing Monday, November 9, 2026

3:50 AM → 4:40 PM
12h 50m • 1 change
4:40 AM → 5:34 PM
12h 54m • 1 change
6:10 AM → 6:25 PM
12h 15m • 1 change
6:30 PM → 6:10 AM
Arrives next day
11h 40m • 1 change
Show more

Departing Tuesday, November 10, 2026

3:50 AM → 4:40 PM
12h 50m • 1 change
4:40 AM → 5:34 PM
12h 54m • 1 change
6:10 AM → 6:25 PM
12h 15m • 1 change
6:30 PM → 6:10 AM
Arrives next day
11h 40m • 1 change
Show more

Departing Wednesday, November 11, 2026

3:35 AM → 4:40 PM
13h 5m • 1 change
4:40 AM → 5:34 PM
12h 54m • 1 change
6:10 AM → 6:25 PM
12h 15m • 1 change
6:30 PM → 6:10 AM
Arrives next day
11h 40m • 1 change

Departing Thursday, November 12, 2026

3:35 AM → 4:40 PM
13h 5m • 1 change
4:40 AM → 5:34 PM
12h 54m • 1 change
6:00 AM → 6:25 PM
12h 25m • 1 change
6:30 PM → 6:10 AM
Arrives next day
11h 40m • 1 change

Frequently asked questions

Want to know about travelling from Florence to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.