The average bus between Florence and Castel Sant'Angelo takes 7h 13m and the fastest bus takes 5h 48m. The bus service runs several times per day from Florence to Castel Sant'Angelo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Florence and Castel Sant'Angelo. The earliest departure is at 3:35 AM at night, and the last departure from Florence is at 7:45 PM which arrives into Castel Sant'Angelo at 6:10 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 7h 13m. The schedules shown below are for the next available departures.


6h 50m • 2 changes

6h 49m • 2 changes

6h 32m • 2 changes

5h 48m • 2 changes

6h 50m • 2 changes

6h 49m • 2 changes

6h 32m • 2 changes

5h 48m • 2 changes

7h 5m • 2 changes

6h 49m • 2 changes

6h 32m • 2 changes

6h 22m • 2 changes

7h 5m • 2 changes

6h 49m • 2 changes

6h 32m • 2 changes

6h 37m • 2 changes

6h 50m • 2 changes

6h 49m • 2 changes

6h 32m • 2 changes

5h 48m • 2 changesWant to know about travelling from Florence to Castel Sant'Angelo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Castel Sant'Angelo. However, there are services departing from Florence Villa Constanza Bus Station and arriving at RIETI | Stazione FS Ist. Superiore Principessa di Napoli # f1070 station via Roma, Autostazione Tiburtina station. The journey, including transfers, takes approximately 7h 13m.
Florence to Castel Sant'Angelo bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Castel Sant'Angelo bus services, operated by Cotral S.p.A., arrive at RIETI | Stazione FS Ist. Superiore Principessa di Napoli # f1070 station.
The distance between Florence and Castel Sant'Angelo is 211.1 km. The road distance is 278 km.
You can take a bus from Florence Villa Constanza Bus Station to CASTEL S. ANGELO | Cantera # f9232 via Roma, Autostazione Tiburtina and RIETI | Stazione FS Ist. Superiore Principessa di Napoli # f1070 in around 6h 59m.