The average bus between Florence and Comiso takes 21h 47m and the fastest bus takes 18h 55m. The bus service runs several times per day from Florence to Comiso. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Florence and Comiso. The earliest departure is at 4:40 AM at night, and the last departure from Florence is at 6:00 PM which arrives into Comiso at 12:55 PM. All services require a transfer at Catania Airport and take an average of 21h 47m. The schedules shown below are for the next available departures.
Arrives next day


25h 15m • 2 changes
Arrives next day


18h 55m • 2 changes
Arrives next day


25h 15m • 2 changes
Arrives next day


18h 55m • 2 changes
Arrives next day


25h 15m • 2 changes
Arrives next day


18h 55m • 2 changes
Arrives next day


25h 15m • 2 changes
Arrives next day


18h 55m • 2 changes
Want to know about travelling from Florence to Comiso? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Comiso. However, there are services departing from Florence station and arriving at Comiso station via Catania Airport. The journey, including transfers, takes approximately 21h 47m.
Florence to Comiso bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Comiso bus services, operated by FlixBus, arrive at Ragusa Bus Terminal station.
Book your Florence to Comiso bus tickets online with FlixBus, Interbus and Azienda Siciliana Trasporti.
The distance between Florence and Comiso is 810.9 km. The road distance is 1,181 km.
You can take a bus from Florence Villa Constanza Bus Station to Comiso via Catania Airport, Aeroporto Vincenzo Bellini/Fontanarossa, and Ragusa in around 18h 28m.