The average bus between Florence and Guidonia takes 4h 54m and the fastest bus takes 4h 20m. The bus service runs several times per day from Florence to Guidonia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Florence and Guidonia. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 4:45 PM which arrives into Guidonia at 10:11 PM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 54m. The schedules shown below are for the next available departures.


5h 16m • 2 changes

4h 50m • 2 changes

4h 20m • 2 changes

4h 58m • 2 changesWant to know about travelling from Florence to Guidonia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Guidonia. However, there are services departing from Florence Villa Constanza Bus Station and arriving at Roma, Autostazione Tiburtina station via Roma, Autostazione Tiburtina station. The journey, including transfers, takes approximately 4h 54m.
Florence to Guidonia bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Guidonia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Florence and Guidonia is 232.1 km. The road distance is 270 km.
FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route.