Florence to Hotel Ponte Sisto, Rome Buses

Florence to Hotel Ponte Sisto, Rome buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Florence and Hotel Ponte Sisto, Rome takes 4h 24m and the fastest bus takes 3h 45m. There is a bus service every few hours from Florence to Hotel Ponte Sisto, Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 24m
Duration: 285 km
Distance: €30
Average price: Hourly
Frequency

Bus

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...

4h 12m

€16–44

Florence to Hotel Ponte Sisto, Rome bus times

Buses run hourly between Florence and Hotel Ponte Sisto, Rome. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Hotel Ponte Sisto, Rome at 5:41 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 24m. The schedules shown below are for the next available departures.

Departing Tuesday, October 13, 2026

7:45 AM → 12:17 PM
4h 32m • 1 change
9:00 AM → 12:59 PM
3h 59m • 1 change
10:05 AM → 2:09 PM
4h 4m • 1 change
10:35 AM → 2:40 PM
4h 5m • 1 change
Show more

Departing Wednesday, October 14, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
4:40 AM → 9:33 AM
4h 53m • 1 change
6:00 AM → 10:15 AM
4h 15m • 1 change
6:10 AM → 10:28 AM
4h 18m • 1 change
Show more

Departing Thursday, October 15, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
4:40 AM → 9:33 AM
4h 53m • 1 change
6:00 AM → 10:15 AM
4h 15m • 1 change
6:10 AM → 10:28 AM
4h 18m • 1 change
Show more

Departing Friday, October 16, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
3:50 AM → 7:51 AM
4h 1m • 1 change
4:40 AM → 9:33 AM
4h 53m • 1 change

Frequently asked questions

Want to know about travelling from Florence to Hotel Ponte Sisto, Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Florence, Italy and Hotel Ponte Sisto, Rome, Italy?

FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €23–35 and the journey takes 3h 15m. Three other operators also service this route.

Operators

Florence to Hotel Ponte Sisto, Rome buses

Find Transport to Hotel Ponte Sisto, Rome

Trip Overview

Bus

Florence to Hotel Ponte Sisto, Rome bus times

Departing Tuesday, October 13, 2026

7:45 AM → 12:17 PM

9:00 AM → 12:59 PM

10:05 AM → 2:09 PM

10:35 AM → 2:40 PM

Departing Wednesday, October 14, 2026

2:20 AM → 6:41 AM

4:40 AM → 9:33 AM

6:00 AM → 10:15 AM

6:10 AM → 10:28 AM

Departing Thursday, October 15, 2026

2:20 AM → 6:41 AM

4:40 AM → 9:33 AM

6:00 AM → 10:15 AM

6:10 AM → 10:28 AM

Departing Friday, October 16, 2026

2:20 AM → 6:41 AM

3:50 AM → 7:51 AM

4:40 AM → 9:33 AM

Frequently asked questions

What companies run services between Florence, Italy and Hotel Ponte Sisto, Rome, Italy?

Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina

Bus trips from Florence

Bus trips to Hotel Ponte Sisto, Rome

Alternative transport options