Florence to Hotel Ponte Sisto, Rome Buses

Florence to Hotel Ponte Sisto, Rome buses

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Trip Overview

The average bus between Florence and Hotel Ponte Sisto, Rome takes 4h 22m and the fastest bus takes 3h 44m. There is a bus service every few hours from Florence to Hotel Ponte Sisto, Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 22m
Duration: 285 km
Distance: €30
Average price: Hourly
Frequency

Bus

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...

4h 12m

€16–44

Florence to Hotel Ponte Sisto, Rome bus times

Buses run hourly between Florence and Hotel Ponte Sisto, Rome. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Hotel Ponte Sisto, Rome at 5:46 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 22m. The schedules shown below are for the next available departures.

Departing Wednesday, October 14, 2026

11:45 AM → 3:57 PM
4h 12m • 1 change
1:05 PM → 5:28 PM
4h 23m • 1 change
2:10 PM → 6:36 PM
4h 26m • 1 change
3:35 PM → 7:37 PM
4h 2m • 1 change
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Departing Thursday, October 15, 2026

2:20 AM → 6:40 AM
4h 20m • 1 change
3:35 AM → 7:37 AM
4h 2m • 1 change
4:40 AM → 9:33 AM
4h 53m • 1 change
6:00 AM → 10:14 AM
4h 14m • 1 change
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Departing Friday, October 16, 2026

2:20 AM → 6:40 AM
4h 20m • 1 change
3:35 AM → 7:37 AM
4h 2m • 1 change
3:50 AM → 7:51 AM
4h 1m • 1 change
4:40 AM → 9:33 AM
4h 53m • 1 change
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Departing Saturday, October 17, 2026

2:20 AM → 6:49 AM
4h 29m • 1 change
3:50 AM → 7:45 AM
3h 55m • 1 change
4:40 AM → 9:21 AM
4h 41m • 1 change
6:10 AM → 10:06 AM
3h 56m • 1 change
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Frequently asked questions

Want to know about travelling from Florence to Hotel Ponte Sisto, Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.