Rome2Rio

Florence to Hotel Ponte Sisto, Rome buses

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Trip Overview

The average bus between Florence and Hotel Ponte Sisto, Rome takes 4h 19m and the fastest bus takes 3h 44m. There is a bus service every few hours from Florence to Hotel Ponte Sisto, Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 19m
Duration
285 km
Distance
€33
Average price
Hourly
Frequency

Florence to Hotel Ponte Sisto, Rome bus times

Buses run hourly between Florence and Hotel Ponte Sisto, Rome. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Hotel Ponte Sisto, Rome at 5:41 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 19m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    FlixBusATAC S.p.A. Azienda per la mobilità7h 41m • 1 change

Departing Wednesday, November 11, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 20m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 2m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 53m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 14m • 1 change
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Departing Thursday, November 12, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 20m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 2m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 53m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 14m • 1 change
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Departing Friday, November 13, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 20m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 2m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 1m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 53m • 1 change
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Departing Saturday, November 14, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 29m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità3h 55m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 41m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità3h 56m • 1 change
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Departing Sunday, November 15, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 26m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità3h 58m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità3h 56m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 37m • 1 change
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Departing Monday, November 16, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 21m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 4m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 1m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 53m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Florence to Hotel Ponte Sisto, Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Florence to Hotel Ponte Sisto, Rome.ExpandLaunch map view
  • Distance: 285.5 km
  • Duration: 4h 19m

What companies run services between Florence, Italy and Hotel Ponte Sisto, Rome, Italy?

FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route.

Operators