Florence to Hotel Ponte Sisto, Rome Buses

Florence to Hotel Ponte Sisto, Rome buses

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Trip Overview

The average bus between Florence and Hotel Ponte Sisto, Rome takes 4h 22m and the fastest bus takes 3h 41m. There is a bus service every few hours from Florence to Hotel Ponte Sisto, Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 22m
Duration: 284 km
Distance: €31
Average price: Hourly
Frequency

Bus

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...

4h 8m

€16–44

Florence to Hotel Ponte Sisto, Rome bus times

Buses run hourly between Florence and Hotel Ponte Sisto, Rome. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Hotel Ponte Sisto, Rome at 5:57 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 22m. The schedules shown below are for the next available departures.

Departing Tuesday, October 20, 2026

6:10 AM → 10:16 AM
4h 6m • 1 change
7:45 AM → 12:12 PM
4h 27m • 1 change
9:00 AM → 12:50 PM
3h 50m • 1 change
10:05 AM → 2:09 PM
4h 4m • 1 change
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Departing Wednesday, October 21, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
3:35 AM → 7:39 AM
4h 4m • 1 change
4:40 AM → 9:36 AM
4h 56m • 1 change
6:10 AM → 10:16 AM
4h 6m • 1 change
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Departing Thursday, October 22, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
3:35 AM → 7:39 AM
4h 4m • 1 change
4:40 AM → 9:36 AM
4h 56m • 1 change
6:10 AM → 10:16 AM
4h 6m • 1 change
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Departing Friday, October 23, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
3:35 AM → 7:39 AM
4h 4m • 1 change
3:50 AM → 7:54 AM
4h 4m • 1 change

Frequently asked questions

Want to know about travelling from Florence to Hotel Ponte Sisto, Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Florence, Italy and Hotel Ponte Sisto, Rome, Italy?

FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €23–40 and the journey takes 3h 15m. Three other operators also service this route.

Operators