The average bus between Florence and Lazio takes 3h 57m and the fastest bus takes 3h 28m. There is a bus service every few hours from Florence to Lazio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Florence and Lazio. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Lazio at 2:56 AM. All services require a transfer at Rome Tiburtina Largo Mazzoni and take an average of 3h 57m. The schedules shown below are for the next available departures.

4h 17m • 1 change

3h 39m • 1 change

4h 28m • 1 change

3h 35m • 1 change

4h 14m • 1 change

3h 45m • 1 change

4h 30m • 1 change

3h 50m • 1 change

4h 14m • 1 change

3h 45m • 1 change

4h 30m • 1 change

3h 50m • 1 change
Want to know about travelling from Florence to Lazio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Lazio. However, there are services departing from Florence station and arriving at Lazio station via Rome Tiburtina Largo Mazzoni. The journey, including transfers, takes approximately 3h 57m.
Florence to Lazio bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Lazio bus services, operated by FlixBus, arrive at Rome Tiburtina Largo Mazzoni station.
Book your Florence to Lazio bus tickets online with FlixBus, ATAC S.p.A. Azienda per la mobilità and 2 other operators.
The distance between Florence and Lazio is 235.2 km. The road distance is 280 km.
Itabus S.p.A. operates a bus from Florence Villa Constanza Bus Station to Rome Tiburtina Largo Mazzoni once daily. Tickets cost €17–40 and the journey takes 3h 20m.