The average bus between Florence and Manciano takes 7h 21m and the fastest bus takes 3h 52m. The bus service runs several times per day from Florence to Manciano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Florence and Manciano. The earliest departure is at 10:09 AM in the morning, and the last departure from Florence is at 7:39 PM which arrives into Manciano at 10:49 AM. All services require a transfer at Grosseto and take an average of 7h 21m. The schedules shown below are for the next available departures.


4h 36m • 2 changes


3h 52m • 2 changes
Arrives next day


15h 10m • 2 changes


4h 36m • 2 changes


3h 52m • 2 changes
Arrives next day


15h 10m • 2 changes
Want to know about travelling from Florence to Manciano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Manciano. However, there are services departing from Florence station and arriving at Manciano station via Grosseto. The journey, including transfers, takes approximately 7h 21m.
Florence to Manciano bus services, operated by Autolinee Toscane, depart from Florence Villa Constanza Bus Station.
Florence to Manciano bus services, operated by Autolinee Toscane, arrive at Manciano Mps station.
The distance between Florence and Manciano is 134.3 km. The road distance is 225 km.
You can take a bus from Florence Villa Constanza Bus Station to Manciano Mps via Grosseto, Grosseto, Orbetello-Monte Arg., and Orbetello Stazione Fs in around 5h 6m.