The average bus between Florence and Marco Simone takes 4h 48m and the fastest bus takes 3h 54m. There is a bus service every few hours from Florence to Marco Simone. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Florence and Marco Simone. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Marco Simone at 6:51 AM. All services require a transfer, and take on average 4h 48m. The schedules shown below are for the next available departures.

4h 51m • 1 change

4h 46m • 1 change

4h 6m • 1 change

4h 21m • 1 change

5h 11m • 1 change

4h 41m • 1 change

4h 51m • 1 change

4h 21m • 1 change

5h 11m • 1 change

4h 56m • 1 change

4h 51m • 1 change

4h 21m • 1 change

5h 11m • 1 change

4h 56m • 1 change

4h 51m • 1 change

4h 21m • 1 change
Want to know about travelling from Florence to Marco Simone? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Marco Simone. However, there are services departing from Florence station and arriving at Marco Simone station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 48m.
Florence to Marco Simone bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Marco Simone bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Florence and Marco Simone is 232.2 km. The road distance is 294 km.
FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €23–40 and the journey takes 3h 15m. Three other operators also service this route.