The average bus between Florence and Marco Simone takes 4h 52m and the fastest bus takes 3h 54m. The bus service runs several times per day from Florence to Marco Simone. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Florence and Marco Simone. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Marco Simone at 6:39 AM. All services require a transfer, and take on average 4h 52m. The schedules shown below are for the next available departures.

4h 46m • 1 change

4h 26m • 1 change

4h 51m • 1 change

4h 31m • 1 change

4h 59m • 1 change

4h 39m • 1 change

4h 9m • 1 change

4h 29m • 1 change

4h 59m • 1 change

4h 39m • 1 change

4h 9m • 1 change

4h 29m • 1 change

4h 59m • 1 change

4h 39m • 1 change

4h 9m • 1 change

5h 44m • 1 change

4h 59m • 1 change

4h 39m • 1 change

4h 9m • 1 change

5h 44m • 1 change
Want to know about travelling from Florence to Marco Simone? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Marco Simone. However, there are services departing from Florence station and arriving at Marco Simone station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 52m.
Florence to Marco Simone bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Marco Simone bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Florence and Marco Simone is 232.2 km. The road distance is 294 km.
FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €21–35 and the journey takes 3h 15m. Three other operators also service this route.