The average bus between Florence and Marco Simone takes 4h 40m and the fastest bus takes 3h 56m. There is a bus service every few hours from Florence to Marco Simone. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Florence and Marco Simone. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Marco Simone at 6:24 AM. All services require a transfer, and take on average 4h 40m. The schedules shown below are for the next available departures.

4h 11m • 1 change
4h 46m • 1 change
3h 56m • 1 change
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4h 41m • 1 change
4h 11m • 1 change
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4h 31m • 1 change
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4h 11m • 1 change
4h 59m • 1 change
4h 39m • 1 change
4h 9m • 1 change
4h 29m • 1 change
4h 56m • 1 change
5h 26m • 1 change
4h 51m • 1 change
4h 36m • 1 change
4h 54m • 1 change
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4h 11m • 1 change
4h 54m • 1 change
4h 31m • 1 change
4h 41m • 1 change
4h 11m • 1 changeWant to know about travelling from Florence to Marco Simone? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Marco Simone. The journey, including transfers, takes approximately 4h 40m.
Florence to Marco Simone bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Marco Simone bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Florence and Marco Simone is 232.2 km. The road distance is 269 km.
FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €23–40 and the journey takes 3h 15m. Three other operators also service this route.