The average bus between Florence and Marsciano takes 5h 36m and the fastest bus takes 3h 26m. The bus service runs several times per day from Florence to Marsciano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Florence and Marsciano. The earliest departure is at 9:00 AM in the morning, and the last departure from Florence is at 9:35 PM which arrives into Marsciano at 7:11 AM. All services require a transfer, and take on average 5h 36m. The schedules shown below are for the next available departures.

5h 1m • 1 change
3h 26m • 1 change
3h 41m • 1 changeArrives next day

13h 1m • 1 change
5h 1m • 1 change
4h 16m • 1 changeArrives next day

9h 36m • 1 change
5h 1m • 1 change
3h 41m • 1 changeArrives next day

9h 36m • 1 changeWant to know about travelling from Florence to Marsciano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Marsciano. However, there are services departing from Florence station and arriving at Marsciano station via Perugia. The journey, including transfers, takes approximately 5h 36m.
Florence to Marsciano bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Marsciano bus services, operated by FlixBus, arrive at Bivio Collepepe station.
The distance between Florence and Marsciano is 130.7 km. The road distance is 181 km.
You can take a bus from Florence Villa Constanza Bus Station to Bivio Collepepe via Perugia in around 3h 56m.