The average bus between Florence and Palermo takes 17h 7m and the fastest bus takes 17h. The bus service runs several times per day from Florence to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Florence and Palermo. The earliest departure is at 6:00 PM in the evening, and the last departure from Florence is at 10:00 PM which arrives into Palermo at 3:15 PM. All services run direct with no transfers required, and take on average 17h 7m. The schedules shown below are for the next available departures.
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Want to know about travelling from Florence to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Florence station and arriving at Palermo station. Services depart twice daily, and operate Once daily. The journey takes approximately 17h 7m.
Florence to Palermo bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Palermo bus services, operated by FlixBus, arrive at Palermo station.
Book your Florence to Palermo bus tickets online with FlixBus.
The distance between Florence and Palermo is 651.9 km. The road distance is 1,274 km.
FlixBus operates a bus from Florence Villa Constanza Bus Station to Palermo twice daily. Tickets cost €100–180 and the journey takes 17h.