The average bus between Florence and Piazza Di Spagna takes 4h 2m and the fastest bus takes 3h 22m. There is a bus service every few hours from Florence to Piazza Di Spagna. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Florence and Piazza Di Spagna. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Piazza Di Spagna at 5:37 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 2m. The schedules shown below are for the next available departures.

3h 36m • 1 change

3h 39m • 1 change

3h 39m • 1 change

3h 38m • 1 change

4h 13m • 1 change

3h 52m • 1 change

3h 42m • 1 change

4h 32m • 1 change

4h 13m • 1 change

3h 52m • 1 change

3h 42m • 1 change

4h 32m • 1 change
Want to know about travelling from Florence to Piazza Di Spagna? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Piazza Di Spagna. However, there are services departing from Florence station and arriving at Piazza Di Spagna station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 2m.
Florence to Piazza Di Spagna bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Piazza Di Spagna bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Florence and Piazza Di Spagna is 231.4 km. The road distance is 282 km.
FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €24–45 and the journey takes 3h 15m. Three other operators also service this route.