The average bus between Florence and Roma Termini takes 3h 58m and the fastest bus takes 3h 28m. There is a bus service every few hours from Florence to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Florence and Roma Termini. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Roma Termini at 3:09 AM. All services require a transfer, and take on average 3h 58m. The schedules shown below are for the next available departures.

3h 56m • 1 change
4h 21m • 1 change
3h 57m • 1 change
3h 44m • 1 change
4h 14m • 1 change
4h • 1 change
4h 30m • 1 change
3h 50m • 1 change
4h 14m • 1 change
3h 45m • 1 change
4h 30m • 1 change
3h 50m • 1 changeWant to know about travelling from Florence to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Roma Termini. However, there are services departing from Florence station and arriving at Roma Termini station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 3h 58m.
Florence to Roma Termini bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Roma Termini bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Florence and Roma Termini is 232.6 km. The road distance is 281 km.
FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €23–35 and the journey takes 3h 15m. Three other operators also service this route.