Florence to Rome Vatican Buses

Florence to Rome Vatican buses

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Trip Overview

The average bus between Florence and Rome Vatican takes 4h 15m and the fastest bus takes 3h 44m. There is a bus service every few hours from Florence to Rome Vatican. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 15m
Duration: 286 km
Distance: €33
Average price: Hourly
Frequency

Bus

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...

4h 9m

€15–46

Florence to Rome Vatican bus times

Buses run hourly between Florence and Rome Vatican. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Rome Vatican at 5:42 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 15m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

8:05 PM → 12:24 AM
Arrives next day
4h 19m • 1 change
11:10 PM → 5:42 AM
Arrives next day
6h 32m • 1 change

Departing Tuesday, November 10, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
3:35 AM → 7:36 AM
4h 1m • 1 change
3:50 AM → 7:45 AM
3h 55m • 1 change
4:40 AM → 9:21 AM
4h 41m • 1 change
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Departing Wednesday, November 11, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
3:35 AM → 7:36 AM
4h 1m • 1 change
4:40 AM → 9:21 AM
4h 41m • 1 change
6:00 AM → 9:55 AM
3h 55m • 1 change
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Departing Thursday, November 12, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
3:35 AM → 7:36 AM
4h 1m • 1 change
4:40 AM → 9:21 AM
4h 41m • 1 change
6:00 AM → 9:55 AM
3h 55m • 1 change
Show more

Departing Friday, November 13, 2026

2:20 AM → 6:41 AM
4h 21m • 1 change
3:35 AM → 7:36 AM
4h 1m • 1 change
3:50 AM → 7:45 AM
3h 55m • 1 change
4:40 AM → 9:21 AM
4h 41m • 1 change
Show more

Departing Saturday, November 14, 2026

2:20 AM → 6:45 AM
4h 25m • 1 change
3:35 AM → 7:33 AM
3h 58m • 1 change
3:50 AM → 7:45 AM
3h 55m • 1 change
4:40 AM → 9:20 AM
4h 40m • 1 change
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Departing Sunday, November 15, 2026

2:20 AM → 6:48 AM
4h 28m • 1 change
3:50 AM → 7:37 AM
3h 47m • 1 change
4:40 AM → 9:31 AM
4h 51m • 1 change
6:10 AM → 10:13 AM
4h 3m • 1 change
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Frequently asked questions

Want to know about travelling from Florence to Rome Vatican? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.