Bus Florence to Rome Vatican from €33 | Tickets & Timetables

Florence to Rome Vatican buses

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Trip Overview

The average bus between Florence and Rome Vatican takes 4h 18m and the fastest bus takes 3h 48m. There is a bus service every few hours from Florence to Rome Vatican. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 18m
Duration: 285 km
Distance: €33
Average price: Hourly
Frequency

Bus

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...

4h 5m

€18–52

Florence to Rome Vatican bus times

Buses run hourly between Florence and Rome Vatican. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Rome Vatican at 5:47 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 18m. The schedules shown below are for the next available departures.

Departing Saturday, August 15, 2026

5:05 PM → 9:27 PM
4h 22m • 1 change
6:30 PM → 11:10 PM
4h 40m • 1 change
7:45 PM → 11:35 PM
3h 50m • 1 change
8:25 PM → 12:27 AM
Arrives next day
4h 2m • 1 change
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Departing Sunday, August 16, 2026

2:20 AM → 6:59 AM
4h 39m • 1 change
3:35 AM → 7:33 AM
3h 58m • 1 change
3:50 AM → 8:05 AM
4h 15m • 1 change
4:40 AM → 9:22 AM
4h 42m • 1 change
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Departing Monday, August 17, 2026

2:20 AM → 6:54 AM
4h 34m • 1 change
3:35 AM → 7:38 AM
4h 3m • 1 change
3:50 AM → 7:52 AM
4h 2m • 1 change
4:40 AM → 9:25 AM
4h 45m • 1 change
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Departing Tuesday, August 18, 2026

2:20 AM → 6:54 AM
4h 34m • 1 change
3:35 AM → 7:38 AM
4h 3m • 1 change
3:50 AM → 7:52 AM
4h 2m • 1 change
4:40 AM → 9:25 AM
4h 45m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Florence to Rome Vatican? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.