The average bus between Florence and San Donato Milanese takes 4h 27m and the fastest bus takes 3h 43m. The bus service runs several times per day from Florence to San Donato Milanese. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Florence and San Donato Milanese. The earliest departure is at 1:50 AM at night, and the last departure from Florence is at 7:45 PM which arrives into San Donato Milanese at 11:28 PM. All services require a transfer, and take on average 4h 27m. The schedules shown below are for the next available departures.

4h 14m • 1 change

3h 49m • 1 change

4h 25m • 1 change

4h 5m • 1 change

4h 14m • 1 change

3h 49m • 1 change

4h 25m • 1 change

4h 58m • 1 change

4h 14m • 1 change

4h 24m • 1 change

4h 25m • 1 change

5h 13m • 1 change

4h 14m • 1 change

3h 49m • 1 change

4h 25m • 1 change

5h 13m • 1 change

4h 14m • 1 change

3h 49m • 1 change

4h 25m • 1 change

4h 5m • 1 change

4h 18m • 1 change

3h 56m • 1 change

4h 24m • 1 change

4h 23m • 1 change
Want to know about travelling from Florence to San Donato Milanese? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to San Donato Milanese. However, there are services departing from Florence station and arriving at San Donato Milanese station via Milano, San Donato M3. The journey, including transfers, takes approximately 4h 27m.
Florence to San Donato Milanese bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to San Donato Milanese bus services, operated by FlixBus, arrive at Milano, San Donato M3 station.
The distance between Florence and San Donato Milanese is 239.6 km. The road distance is 296 km.
FlixBus operates a bus from Florence Villa Constanza Bus Station to Milano, San Donato M3 every 3 hours. Tickets cost €24–40 and the journey takes 3h 25m. Two other operators also service this route.