The average bus between Florence and San Vito Lo Capo takes 27h 39m and the fastest bus takes 20h 50m. The bus service runs several times per day from Florence to San Vito Lo Capo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Florence and San Vito Lo Capo. The earliest departure is at 6:00 PM in the evening, and the last departure from Florence is at 10:00 PM which arrives into San Vito Lo Capo at 9:50 AM. All services require a transfer at Palermo and take an average of 27h 39m. The schedules shown below are for the next available departures.
Arrives next day

20h 50m • 1 change
Arrives +2 days

35h 50m • 1 change
Arrives next day

20h 50m • 1 change
Arrives +2 days

35h 50m • 1 change
Arrives next day

20h 50m • 1 change
Arrives +2 days

35h 50m • 1 change
Arrives next day

20h 50m • 1 change
Arrives +2 days

35h 50m • 1 change
Want to know about travelling from Florence to San Vito Lo Capo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to San Vito Lo Capo. However, there are services departing from Florence station and arriving at San Vito Lo Capo station via Palermo. The journey, including transfers, takes approximately 27h 39m.
Florence to San Vito Lo Capo bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to San Vito Lo Capo bus services, operated by FlixBus, arrive at Via Piersanti Mattarella, San Vito Lo Capo station.
The distance between Florence and San Vito Lo Capo is 635.8 km. The road distance is 1,387 km.
You can take a bus from Florence Villa Constanza Bus Station to Via Piersanti Mattarella, San Vito Lo Capo via Palermo and Palermo Centrale Station in around 20h 5m.