Rome2Rio

Florence to Sicily buses

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Trip Overview

The average bus between Florence and Sicily takes 17h 31m and the fastest bus takes 17h 23m. There is at least one bus per day from Florence to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 31m
Duration
1,278 km
Distance
€136
Average price
Once daily
Frequency

Florence to Sicily bus times

Buses run once daily between Florence and Sicily. The earliest departure is at 6:00 PM in the evening, and the last departure from Florence is at 10:00 PM which arrives into Sicily at 3:43 PM. All services require a transfer at Palermo and take an average of 17h 31m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 23m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 23m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 23m • 1 change
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    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 43m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 27m • 1 change
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    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 42m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 23m • 1 change
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    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 43m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 23m • 1 change
  •  → 

    Arrives next day

    FlixBusAMAT Palermo S.p.A.17h 43m • 1 change

Frequently asked questions

Want to know about travelling from Florence to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Florence to Sicily.ExpandLaunch map view
  • Distance: 1,278.4 km
  • Duration: 17h 31m

What companies run services between Florence, Italy and Sicily, Italy?

FlixBus operates a bus from Florence Villa Constanza Bus Station to Palermo twice daily. Tickets cost €110–170 and the journey takes 17h.

Operators