Bus Florence to St. Simon from €33 | Tickets & Timetables

Trip Overview

The average bus between Florence and St. Simon takes 4h 32m and the fastest bus takes 3h 57m. There is a bus service every few hours from Florence to St. Simon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 32m
Duration: 287 km
Distance: €33
Average price: Hourly
Frequency

Bus

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...

4h 21m

€18–52

Florence to St. Simon bus times

Buses run hourly between Florence and St. Simon. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into St. Simon at 6:02 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 32m. The schedules shown below are for the next available departures.

Departing Monday, August 10, 2026

2:10 PM → 6:40 PM
4h 30m • 1 change
3:35 PM → 7:45 PM
4h 10m • 1 change
5:05 PM → 9:29 PM
4h 24m • 1 change
6:30 PM → 11:22 PM
4h 52m • 1 change
Show more

Departing Tuesday, August 11, 2026

2:20 AM → 6:58 AM
4h 38m • 1 change
3:50 AM → 7:55 AM
4h 5m • 1 change
4:40 AM → 9:37 AM
4h 57m • 1 change
6:10 AM → 10:19 AM
4h 9m • 1 change
Show more

Departing Wednesday, August 12, 2026

2:20 AM → 6:58 AM
4h 38m • 1 change
3:35 AM → 7:55 AM
4h 20m • 1 change
4:40 AM → 9:37 AM
4h 57m • 1 change
6:10 AM → 10:19 AM
4h 9m • 1 change
Show more

Departing Thursday, August 13, 2026

2:20 AM → 6:58 AM
4h 38m • 1 change
3:35 AM → 7:55 AM
4h 20m • 1 change
4:40 AM → 9:37 AM
4h 57m • 1 change
6:10 AM → 10:19 AM
4h 9m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Florence to St. Simon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Florence, Italy and St. Simon, Vatican City?

FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €23–40 and the journey takes 3h 15m. Three other operators also service this route.

Operators