Florence to St. Simon Buses

Trip Overview

The average bus between Florence and St. Simon takes 4h 37m and the fastest bus takes 3h 57m. There is a bus service every few hours from Florence to St. Simon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 37m
Duration: 287 km
Distance: €31
Average price: Hourly
Frequency

Bus

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...

4h 22m

€16–44

Florence to St. Simon bus times

Buses run hourly between Florence and St. Simon. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into St. Simon at 6:02 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 37m. The schedules shown below are for the next available departures.

Departing Friday, October 23, 2026

2:20 AM → 6:50 AM
4h 30m • 1 change
3:35 AM → 7:50 AM
4h 15m • 1 change
3:50 AM → 8:05 AM
4h 15m • 1 change
4:40 AM → 9:50 AM
5h 10m • 1 change
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Departing Saturday, October 24, 2026

2:20 AM → 6:58 AM
4h 38m • 1 change
3:50 AM → 7:55 AM
4h 5m • 1 change
4:40 AM → 9:37 AM
4h 57m • 1 change
6:10 AM → 10:19 AM
4h 9m • 1 change
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Departing Sunday, October 25, 2026

2:20 AM → 6:01 AM
4h 41m • 1 change
2:35 AM → 6:39 AM
4h 4m • 1 change
2:50 AM → 6:58 AM
4h 8m • 1 change
3:40 AM → 8:24 AM
4h 44m • 1 change
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Departing Monday, October 26, 2026

2:20 AM → 6:50 AM
4h 30m • 1 change
3:35 AM → 7:50 AM
4h 15m • 1 change
3:50 AM → 8:05 AM
4h 15m • 1 change
4:40 AM → 9:50 AM
5h 10m • 1 change
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Departing Tuesday, October 27, 2026

2:20 AM → 6:50 AM
4h 30m • 1 change
3:35 AM → 7:50 AM
4h 15m • 1 change
3:50 AM → 8:05 AM
4h 15m • 1 change
4:40 AM → 9:50 AM
5h 10m • 1 change
Show more

Departing Wednesday, October 28, 2026

2:20 AM → 6:50 AM
4h 30m • 1 change
3:35 AM → 7:50 AM
4h 15m • 1 change
4:40 AM → 9:50 AM
5h 10m • 1 change
6:00 AM → 10:30 AM
4h 30m • 1 change
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Departing Thursday, October 29, 2026

2:20 AM → 6:50 AM
4h 30m • 1 change
3:35 AM → 7:50 AM
4h 15m • 1 change
4:40 AM → 9:50 AM
5h 10m • 1 change
6:00 AM → 10:30 AM
4h 30m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Florence to St. Simon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.