Rome2Rio

Florence to St. Simon buses

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Trip Overview

The average bus between Florence and St. Simon takes 4h 35m and the fastest bus takes 3h 55m. There is a bus service every few hours from Florence to St. Simon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 35m
Duration
287 km
Distance
€33
Average price
Hourly
Frequency

Florence to St. Simon bus times

Buses run hourly between Florence and St. Simon. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into St. Simon at 6:05 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 35m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 57m • 1 change
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    Arrives next day

    FlixBusATAC S.p.A. Azienda per la mobilità6h 55m • 1 change

Departing Friday, November 13, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 29m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 13m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 13m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità5h 7m • 1 change
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Departing Saturday, November 14, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 36m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 4m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 55m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 8m • 1 change
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Departing Sunday, November 15, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 36m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 6m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 12m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 56m • 1 change
  • Show more

Departing Monday, November 16, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 30m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 15m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 15m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità5h 10m • 1 change
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Departing Tuesday, November 17, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 30m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 15m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 15m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità5h 10m • 1 change
  • Show more

Departing Wednesday, November 18, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 30m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 15m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità5h 10m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 30m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Florence to St. Simon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Florence to St. Simon.ExpandLaunch map view
  • Distance: 287.4 km
  • Duration: 4h 35m

What companies run services between Florence, Italy and St. Simon, Vatican City?

FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route.

Operators