Florence to Tmark Hotel Vaticano, Rome Buses

Trip Overview

The average bus between Florence and Tmark Hotel Vaticano, Rome takes 4h 16m and the fastest bus takes 3h 46m. There is a bus service every few hours from Florence to Tmark Hotel Vaticano, Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 16m
Duration: 286 km
Distance: €33
Average price: Hourly
Frequency

Bus

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...

4h 9m

€15–46

Florence to Tmark Hotel Vaticano, Rome bus times

Buses run hourly between Florence and Tmark Hotel Vaticano, Rome. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Tmark Hotel Vaticano, Rome at 5:44 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 16m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

11:15 AM → 3:12 PM
3h 57m • 1 change
11:30 AM → 3:30 PM
4h • 1 change
1:05 PM → 5:36 PM
4h 31m • 1 change
2:10 PM → 6:36 PM
4h 26m • 1 change
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Departing Tuesday, November 10, 2026

2:20 AM → 6:43 AM
4h 23m • 1 change
3:35 AM → 7:38 AM
4h 3m • 1 change
3:50 AM → 7:47 AM
3h 57m • 1 change
4:40 AM → 9:23 AM
4h 43m • 1 change
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Departing Wednesday, November 11, 2026

2:20 AM → 6:43 AM
4h 23m • 1 change
3:35 AM → 7:38 AM
4h 3m • 1 change
4:40 AM → 9:23 AM
4h 43m • 1 change
6:00 AM → 9:57 AM
3h 57m • 1 change
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Departing Thursday, November 12, 2026

2:20 AM → 6:43 AM
4h 23m • 1 change
3:35 AM → 7:38 AM
4h 3m • 1 change
4:40 AM → 9:23 AM
4h 43m • 1 change
6:00 AM → 9:57 AM
3h 57m • 1 change
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Departing Friday, November 13, 2026

2:20 AM → 6:43 AM
4h 23m • 1 change
3:35 AM → 7:38 AM
4h 3m • 1 change
3:50 AM → 7:47 AM
3h 57m • 1 change
4:40 AM → 9:23 AM
4h 43m • 1 change
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Departing Saturday, November 14, 2026

2:20 AM → 6:46 AM
4h 26m • 1 change
3:35 AM → 7:34 AM
3h 59m • 1 change
3:50 AM → 7:46 AM
3h 56m • 1 change
4:40 AM → 9:22 AM
4h 42m • 1 change
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Departing Sunday, November 15, 2026

2:20 AM → 6:50 AM
4h 30m • 1 change
3:50 AM → 7:39 AM
3h 49m • 1 change
4:40 AM → 9:32 AM
4h 52m • 1 change
6:10 AM → 10:14 AM
4h 4m • 1 change
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Frequently asked questions

Want to know about travelling from Florence to Tmark Hotel Vaticano, Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.