Florence to Vatican City Relais, Rome bus times
Buses run hourly between Florence and Vatican City Relais, Rome. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Vatican City Relais, Rome at 5:59 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 26m. The schedules shown below are for the next available departures.
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4h 31m • 1 change
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4h 3m • 1 change
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4h 7m • 1 change
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4h 3m • 1 change
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Departing Wednesday, August 12, 2026
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4h 39m • 1 change
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4h 15m • 1 change
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4h 58m • 1 change
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4h 20m • 1 change
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Departing Thursday, August 13, 2026
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4h 39m • 1 change
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4h 15m • 1 change
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4h 11m • 1 change
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4h 58m • 1 change
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