Rome2Rio

Florence to Vatican Museums buses

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Trip Overview

The average bus between Florence and Vatican Museums takes 4h 19m and the fastest bus takes 3h 48m. There is a bus service every few hours from Florence to Vatican Museums. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 19m
Duration
286 km
Distance
€33
Average price
Hourly
Frequency

Florence to Vatican Museums bus times

Buses run hourly between Florence and Vatican Museums. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Vatican Museums at 5:45 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 19m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 28m • 1 change
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    Arrives next day

    FlixBusATAC S.p.A. Azienda per la mobilità6h 35m • 1 change

Departing Friday, November 13, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 24m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 5m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità3h 59m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 45m • 1 change
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Departing Saturday, November 14, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 28m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 1m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità3h 58m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 44m • 1 change
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Departing Sunday, November 15, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 31m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità3h 50m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 54m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 6m • 1 change
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Departing Monday, November 16, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 30m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 8m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 3m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 46m • 1 change
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Departing Tuesday, November 17, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 30m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 8m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 3m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 46m • 1 change
  • Show more

Departing Wednesday, November 18, 2026

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    FlixBusATAC S.p.A. Azienda per la mobilità4h 30m • 1 change
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    Itabus S.p.A.ATAC S.p.A. Azienda per la mobilità4h 8m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità4h 46m • 1 change
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    FlixBusATAC S.p.A. Azienda per la mobilità3h 58m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Florence to Vatican Museums? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Florence to Vatican Museums.ExpandLaunch map view
  • Distance: 286.2 km
  • Duration: 4h 19m

What companies run services between Florence, Italy and Vatican Museums, Vatican City?

FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route.

Operators