Florence to Vatican Museums Buses

Florence to Vatican Museums buses

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Trip Overview

The average bus between Florence and Vatican Museums takes 4h 18m and the fastest bus takes 3h 45m. There is a bus service every few hours from Florence to Vatican Museums. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 18m
Duration: 285 km
Distance: €30
Average price: Hourly
Frequency

Bus

best

Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...

4h 8m

€16–44

Florence to Vatican Museums bus times

Buses run hourly between Florence and Vatican Museums. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 11:10 PM which arrives into Vatican Museums at 5:44 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 18m. The schedules shown below are for the next available departures.

Departing Wednesday, October 14, 2026

5:05 PM → 9:18 PM
4h 13m • 1 change
6:30 PM → 10:31 PM
4h 1m • 1 change
7:45 PM → 11:40 PM
3h 55m • 1 change
10:00 PM → 5:44 AM
Arrives next day
7h 44m • 1 change

Departing Thursday, October 15, 2026

2:20 AM → 6:43 AM
4h 23m • 1 change
3:35 AM → 7:38 AM
4h 3m • 1 change
4:40 AM → 9:23 AM
4h 43m • 1 change
6:00 AM → 10:06 AM
4h 6m • 1 change
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Departing Friday, October 16, 2026

2:20 AM → 6:43 AM
4h 23m • 1 change
3:35 AM → 7:38 AM
4h 3m • 1 change
3:50 AM → 7:47 AM
3h 57m • 1 change
4:40 AM → 9:23 AM
4h 43m • 1 change
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Departing Saturday, October 17, 2026

2:20 AM → 6:39 AM
4h 19m • 1 change
3:50 AM → 7:35 AM
3h 45m • 1 change
4:40 AM → 9:24 AM
4h 44m • 1 change
6:00 AM → 9:57 AM
3h 57m • 1 change
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Frequently asked questions

Want to know about travelling from Florence to Vatican Museums? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.