The average bus between Florence and Vitignano takes 2h 40m and the fastest bus takes 1h 25m. The bus service runs several times per day from Florence to Vitignano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Florence and Vitignano. The earliest departure is at 4:40 AM at night, and the last departure from Florence is at 6:10 PM which arrives into Vitignano at 7:39 PM. All services require a transfer at Siena and take an average of 2h 40m. The schedules shown below are for the next available departures.

2h 40m • 1 change

2h 25m • 1 change

4h 5m • 1 change

1h 29m • 1 change

2h 40m • 1 change

2h 25m • 1 change

2h 45m • 1 change

4h 5m • 1 change

2h 40m • 1 change

2h 25m • 1 change

2h 45m • 1 change

4h 5m • 1 change

2h 40m • 1 change

2h 25m • 1 change

2h 45m • 1 change

4h 5m • 1 change
Want to know about travelling from Florence to Vitignano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Vitignano. However, there are services departing from Florence station and arriving at Vitignano station via Siena. The journey, including transfers, takes approximately 2h 40m.
Florence to Vitignano bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Vitignano bus services, operated by FlixBus, arrive at San Giovanni station.
The distance between Florence and Vitignano is 48.8 km. The road distance is 76 km.
You can take a bus from Florence Villa Constanza Bus Station to San Giovanni via Siena and Siena Autostazione in around 2h 5m.