The average bus between Florence and Duke University takes 6h 31m and the fastest bus takes 4h 52m. The bus service runs several times per day from Florence to Duke University. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Florence and Duke University. The earliest departure is at 1:25 PM in the afternoon, and the last departure from Florence is at 8:30 PM which arrives into Duke University at 6:12 AM. All services require a transfer at Raleigh Bus Station and take an average of 6h 31m. The schedules shown below are for the next available departures.


5h 17m • 2 changes


4h 52m • 2 changes
Arrives next day


9h 42m • 2 changes


5h 17m • 2 changes


4h 52m • 2 changes
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9h 42m • 2 changes


5h 17m • 2 changes


4h 52m • 2 changes
Arrives next day


10h 42m • 2 changes


5h 17m • 2 changes


4h 52m • 2 changes
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9h 42m • 2 changes


5h 17m • 2 changes


4h 52m • 2 changes
Arrives next day


9h 42m • 2 changes
Want to know about travelling from Florence to Duke University? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Duke University. However, there are services departing from Florence station and arriving at Duke University station via Raleigh Bus Station station. The journey, including transfers, takes approximately 6h 31m.
Florence to Duke University bus services, operated by Jefferson Lines, depart from Florence Bus Station.
Florence to Duke University bus services, operated by Jefferson Lines, arrive at Raleigh Bus Station.
The distance between Florence and Duke University is 214.3 km. The road distance is 282 km.
Jefferson Lines operates a bus from Florence Bus Station to Raleigh Bus Station once daily. Tickets cost $40–60 and the journey takes 2h 55m. Greyhound USA also services this route twice daily.