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Florence to Niagara Falls buses

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Trip Overview

The average bus between Florence and Niagara Falls takes 27h 31m and the fastest bus takes 26h 20m. The bus runs, on average, 3 times per week from Florence to Niagara Falls. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

27h 31m
Duration
1,053 mi
Distance
$199
Average price
3 times a week
Frequency

Florence to Niagara Falls bus times

Buses run 3 times a week between Florence and Niagara Falls. The service departs Florence at 3:20 PM in the afternoon, which arrives into Niagara Falls at 21:15:00. All services require a transfer at Fayetteville Bus Station and take an average of 27h 31m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA29h 55m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA26h 20m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA26h 20m • 2 changes

Frequently asked questions

Want to know about travelling from Florence to Niagara Falls? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Florence to Niagara Falls.ExpandLaunch map view
  • Distance: 1,052.8 mi
  • Duration: 27h 31m

What companies run services between Florence, SC, USA and Niagara Falls, NY, USA?

You can take a bus from Florence Bus Station to Niagara Falls USA via Fayetteville Bus Station and Newark Penn Station in around 22h 5m.

Operators