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Fort Myers to Buffalo buses

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Trip Overview

The average bus between Fort Myers and Buffalo takes 2d and the fastest bus takes 46h 5m. The bus runs, on average, 3 times per week from Fort Myers to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d
Duration
1,701 mi
Distance
$326
Average price
3 times a week
Frequency

Fort Myers to Buffalo bus times

Buses run 3 times a week between Fort Myers and Buffalo. The earliest departure is at 12:20 PM in the afternoon, and the last departure from Fort Myers is at 6:55 PM which arrives into Buffalo at 5:00 PM. All services require a transfer at Orlando Bus Station and take an average of 2d. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA2d 5h • 2 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAFlixbus USA46h 5m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAFlixbus USA46h 5m • 2 changes

Frequently asked questions

Want to know about travelling from Fort Myers to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Fort Myers to Buffalo.ExpandLaunch map view
  • Distance: 1,701.5 mi
  • Duration: 2d

What companies run services between Fort Myers, FL, USA and Buffalo, NY, USA?

You can take a bus from Fort Myers Bus Stop to Buffalo via Orlando Bus Station and Newark Penn Station in around 35h 40m.

Operators