The average bus between Fort Myers and Chicago takes 34h 30m and the fastest bus takes 31h 10m. The bus service runs several times per day from Fort Myers to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Fort Myers and Chicago. The earliest departure is at 12:20 PM in the afternoon, and the last departure from Fort Myers is at 6:55 PM which arrives into Chicago at 8:25 AM. All services require a transfer at Orlando Bus Station and take an average of 34h 30m. The schedules shown below are for the next available departures.
Arrives next day


30h 10m • 2 changes
Arrives +2 days


37h 30m • 2 changes
Arrives next day


30h 10m • 2 changes
Arrives +2 days


37h 30m • 2 changes
Arrives next day


30h 10m • 2 changes
Arrives +2 days


37h 30m • 2 changes
Want to know about travelling from Fort Myers to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Fort Myers to Chicago. However, there are services departing from Fort Myers station and arriving at Chicago station via Orlando Bus Station station. The journey, including transfers, takes approximately 34h 30m.
Fort Myers to Chicago bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Fort Myers to Chicago bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Book your Fort Myers to Chicago bus tickets online with Flixbus USA and Greyhound USA.
The distance between Fort Myers and Chicago is 1,776.5 km. The road distance is 2,211 km.
You can take a bus from Fort Myers Bus Stop to Chicago Bus Station via Orlando Bus Station and Atlanta Bus Station in around 30h 15m.