The average bus between Fort Myers and Florida Keys takes 18h 23m and the fastest bus takes 17h 45m. There is at least one bus per day from Fort Myers to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Fort Myers and Florida Keys. The earliest departure is at 4:45 PM in the afternoon, and the last departure from Fort Myers is at 6:30 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Miami Airport Station and take an average of 18h 23m. The schedules shown below are for the next available departures.
Want to know about travelling from Fort Myers to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Fort Myers to Florida Keys. However, there are services departing from Fort Myers Bus Stop station and arriving at Big Pine Key station via Miami Airport Station. The journey, including transfers, takes approximately 18h 23m.
Fort Myers to Florida Keys bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Fort Myers to Florida Keys bus services, operated by Greyhound USA, arrive at Big Pine Key station.
The distance between Fort Myers and Florida Keys is 221.5 km. The road distance is 416 km.
You can take a bus from Fort Myers Bus Stop to Florida Keys via Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 9h 15m.
