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Fort Myers to Lake Charles buses

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Trip Overview

The average bus between Fort Myers and Lake Charles takes 39h 35m and the fastest bus takes 38h 30m. The bus runs, on average, 6 times per week from Fort Myers to Lake Charles. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

39h 35m
Duration
950 mi
Distance
$194
Average price
6 times a week
Frequency

Fort Myers to Lake Charles bus times

Buses run 6 times a week between Fort Myers and Lake Charles. The service departs Fort Myers at 6:55 PM in the evening, which arrives into Lake Charles at 08:25:00. All services require a transfer at Tampa Bus Station and take an average of 39h 35m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA38h 30m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA38h 30m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA38h 30m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA38h 30m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA38h 30m • 2 changes

Frequently asked questions

Want to know about travelling from Fort Myers to Lake Charles? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Fort Myers to Lake Charles.ExpandLaunch map view
  • Distance: 950.2 mi
  • Duration: 39h 35m

What companies run services between Fort Myers, FL, USA and Lake Charles, LA, USA?

You can take a bus from Fort Myers Bus Stop to Lake Charles via Tampa Bus Station and Tallahassee in around 22h 40m.

Operators