The average bus between Fort Myers and San Antonio takes 47h 36m and the fastest bus takes 45h 25m. The bus runs, on average, 6 times per week from Fort Myers to San Antonio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Fort Myers and San Antonio. The earliest departure is at 12:20 PM in the afternoon, and the last departure from Fort Myers is at 6:55 PM which arrives into San Antonio at 3:20 PM. All services require a transfer at Tampa Bus Station and take an average of 47h 36m. The schedules shown below are for the next available departures.
Want to know about travelling from Fort Myers to San Antonio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Fort Myers to San Antonio. However, there are services departing from Fort Myers station and arriving at San Antonio station via Tampa Bus Station station. The journey, including transfers, takes approximately 47h 36m.
Fort Myers to San Antonio bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Fort Myers to San Antonio bus services, operated by Flixbus USA, arrive at San Antonio Bus Station.
Book your Fort Myers to San Antonio bus tickets online with Flixbus USA and Greyhound USA.
The distance between Fort Myers and San Antonio is 1,662.5 km. The road distance is 2,100 km.
You can take a bus from Fort Myers Bus Stop to San Antonio Bus Station via Tampa Bus Station, Tallahassee, and Houston Bus Station in around 31h 5m.