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Fort Myers to Winston-Salem buses

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Trip Overview

The average bus between Fort Myers and Winston-Salem takes 37h and the fastest bus takes 35h 55m. The bus runs, on average, 6 times per week from Fort Myers to Winston-Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

37h
Duration
817 mi
Distance
$158
Average price
6 times a week
Frequency

Fort Myers to Winston-Salem bus times

Buses run 6 times a week between Fort Myers and Winston-Salem. The service departs Fort Myers at 6:55 PM in the evening, which arrives into Winston-Salem at 06:50:00. All services require a transfer at Orlando Bus Station and take an average of 37h. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA35h 55m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA35h 55m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA35h 55m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA35h 55m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA35h 55m • 2 changes

Frequently asked questions

Want to know about travelling from Fort Myers to Winston-Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Fort Myers to Winston-Salem.ExpandLaunch map view
  • Distance: 816.9 mi
  • Duration: 37h

What companies run services between Fort Myers, FL, USA and Winston-Salem, NC, USA?

You can take a bus from Fort Myers Bus Stop to Winston Salem(Trans Center) via Orlando Bus Station and Charlotte Bus Station in around 18h 25m.

Operators