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Fort Pierce to Winston-Salem buses

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Trip Overview

The average bus between Fort Pierce and Winston-Salem takes 24h 48m and the fastest bus takes 21h 48m. The bus runs, on average, 6 times per week from Fort Pierce to Winston-Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 48m
Duration
721 mi
Distance
$149
Average price
6 times a week
Frequency

Fort Pierce to Winston-Salem bus times

Buses run 6 times a week between Fort Pierce and Winston-Salem. The earliest departure is at 9:02 AM in the morning, and the last departure from Fort Pierce is at 3:02 PM which arrives into Winston-Salem at 6:50 AM. All services require a transfer at Wheeler Ter & Okeechobee Rd and take an average of 24h 48m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Area Regional Transit St LucieRedCoachLynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USA21h 48m • 5 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Area Regional Transit St LucieRedCoachLynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USA21h 48m • 5 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Area Regional Transit St LucieRedCoachLynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USA21h 48m • 5 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Area Regional Transit St LucieRedCoachLynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USA21h 48m • 5 changes
  •  → 

    Arrives +2 days

    Area Regional Transit St LucieRedCoachLynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USA39h 48m • 5 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Area Regional Transit St LucieRedCoachLynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USA21h 48m • 5 changes

Frequently asked questions

Want to know about travelling from Fort Pierce to Winston-Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Fort Pierce to Winston-Salem.ExpandLaunch map view
  • Distance: 721.4 mi
  • Duration: 24h 48m

What companies run services between Fort Pierce, FL, USA and Winston-Salem, NC, USA?

You can take a bus from Orange Ave & N 9th St to Winston Salem(Trans Center) via Wheeler Ter & Okeechobee Rd, Fort Pierce, Mccoy Rd & Gondola Dr, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Charlotte Bus Station in around 18h 2m.

Operators