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Framingham to Buffalo buses

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Trip Overview

The average bus between Framingham and Buffalo takes 32h and the fastest bus takes 31h 50m. The bus runs, on average, 6 times per week from Framingham to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

32h
Duration
461 mi
Distance
$96
Average price
6 times a week
Frequency

Framingham to Buffalo bus times

Buses run 6 times a week between Framingham and Buffalo. The service departs Framingham at 2:45 PM in the afternoon, which arrives into Buffalo at 22:35:00. All services require a transfer, and take on average 32h. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

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    Arrives next day

    Greyhound USAGreyhound USA31h 50m • 1 change

Departing Saturday, October 31, 2026

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    Arrives next day

    Greyhound USAGreyhound USA32h 50m • 1 change

Departing Sunday, November 1, 2026

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    Arrives next day

    Greyhound USAGreyhound USA31h 50m • 1 change

Departing Monday, November 2, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA31h 50m • 1 change

Departing Tuesday, November 3, 2026

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    Arrives next day

    Greyhound USAGreyhound USA31h 50m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA31h 50m • 1 change

Frequently asked questions

Want to know about travelling from Framingham to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Framingham to Buffalo.ExpandLaunch map view
  • Distance: 460.5 mi
  • Duration: 32h

What companies run services between Framingham, MA, USA and Buffalo, NY, USA?

You can take a bus from Framingham to Buffalo via Springfield Union Station in around 10h 55m.

Operators