The average bus between Framingham and Midtown Manhattan takes 6h 10m and the fastest bus takes 4h 55m. The bus service runs several times per day from Framingham to Midtown Manhattan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Framingham and Midtown Manhattan. The earliest departure is at 7:30 AM in the morning, and the last departure from Framingham is at 7:00 PM which arrives into Midtown Manhattan at 5:24 AM. All services require a transfer at Worcester and take an average of 6h 10m. The schedules shown below are for the next available departures.

5h 31m • 1 change
5h 7m • 1 changeArrives next day

10h 20m • 1 change
5h 11m • 1 change
5h 4m • 1 changeArrives next day

5h 9m • 1 change
5h 31m • 1 change
5h 7m • 1 changeArrives next day

10h 24m • 1 changeWant to know about travelling from Framingham to Midtown Manhattan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Framingham to Midtown Manhattan. However, there are services departing from Framingham station and arriving at Midtown Manhattan station via New York. The journey, including transfers, takes approximately 6h 10m.
Framingham to Midtown Manhattan bus services, operated by Flixbus USA, depart from Worcester station.
Framingham to Midtown Manhattan bus services, operated by Flixbus USA, arrive at New York station.
The distance between Framingham and Midtown Manhattan is 272 km. The road distance is 319 km.
Peter Pan Bus Lines operates a bus from Worcester to New York 4 times a day. Tickets cost $35–65 and the journey takes 3h 35m.