The average bus between Frankfurt - Main Bus Station and Prague takes 7h 37m and the fastest bus takes 6h 18m. The bus service runs several times per day from Frankfurt - Main Bus Station to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Frankfurt - Main Bus Station and Prague. The earliest departure is at 6:05 AM in the morning, and the last departure from Frankfurt - Main Bus Station is at 11:59 PM which arrives into Prague at 6:55 AM. All services run direct with no transfers required, and take on average 7h 37m. The schedules shown below are for the next available departures.
Arrives next day
Arrives next day
Want to know about travelling from Frankfurt - Main Bus Station to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Frankfurt - Main Bus Station station and arriving at Prague station. Services depart every 4 hours, and operate Twice daily. The journey takes approximately 7h 37m.
Frankfurt - Main Bus Station to Prague bus services, operated by FlixBus, depart from Frankfurt central train station.
Frankfurt - Main Bus Station to Prague bus services, operated by FlixBus, arrive at Praha, ÚAN Florenc station.
Book your Frankfurt - Main Bus Station to Prague bus tickets online with FlixBus and RegioJet.
The distance between Frankfurt - Main Bus Station and Prague is 410.6 km. The road distance is 520 km.
FlixBus operates a bus from Frankfurt central train station to Praha, ÚAN Florenc every 4 hours. Tickets cost Kč 1,000–1,800 and the journey takes 7h 25m. RegioJet also services this route once daily.