The average bus between Frankfurt(Main)Hbf and Strasbourg Cathedral takes 3h 59m and the fastest bus takes 3h 30m. There is a bus service every few hours from Frankfurt(Main)Hbf to Strasbourg Cathedral. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Frankfurt(Main)Hbf and Strasbourg Cathedral. The earliest departure is at 12:40 AM at night, and the last departure from Frankfurt(Main)Hbf is at 10:45 PM which arrives into Strasbourg Cathedral at 5:30 AM. All services require a transfer at Frankfurt central train station and take an average of 3h 59m. The schedules shown below are for the next available departures.

5h 50m • 1 change

4h 5m • 1 change

2h 15m • 1 change

4h 40m • 1 change

3h 35m • 1 change

4h • 1 change

4h • 1 change

4h • 1 change

3h 35m • 1 change

4h • 1 change

4h • 1 change

4h • 1 change
Want to know about travelling from Frankfurt(Main)Hbf to Strasbourg Cathedral? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Frankfurt(Main)Hbf to Strasbourg Cathedral. However, there are services departing from Frankfurt(Main)Hbf station and arriving at Strasbourg Cathedral station via Karlsruhe central train station station. The journey, including transfers, takes approximately 3h 59m.
Frankfurt(Main)Hbf to Strasbourg Cathedral bus services, operated by FlixBus, depart from Frankfurt central train station.
Frankfurt(Main)Hbf to Strasbourg Cathedral bus services, operated by FlixBus, arrive at Strasbourg station.
Book your Frankfurt(Main)Hbf to Strasbourg Cathedral bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Frankfurt(Main)Hbf and Strasbourg Cathedral is 182.1 km. The road distance is 241 km.
You can take a vehicle from Frankfurt(Main)Hbf to Strasbourg Cathedral via Frankfurt central train station, Karlsruhe central train station, and Strasbourg in around 4h 38m.