The average bus between Frankfurt am Main and Brescia takes 12h 55m and the fastest bus takes 12h 15m. The bus service runs several times per day from Frankfurt am Main to Brescia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Frankfurt am Main and Brescia. The earliest departure is at 5:15 AM in the morning, and the last departure from Frankfurt am Main is at 10:45 PM which arrives into Brescia at 1:35 PM. All services require a transfer, and take on average 12h 55m. The schedules shown below are for the next available departures.

14h 15m • 1 change

15h 40m • 1 change
Arrives next day

14h 50m • 1 change

14h 15m • 1 change

15h 40m • 1 change
Arrives next day

14h 50m • 1 change

14h 15m • 1 change

15h 40m • 1 change
Arrives next day

14h 50m • 1 change

14h 15m • 1 change

15h 40m • 1 change
Arrives next day

14h 50m • 1 change
Want to know about travelling from Frankfurt am Main to Brescia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Frankfurt am Main to Brescia. However, there are services departing from Frankfurt am Main station and arriving at Brescia station via Milan. The journey, including transfers, takes approximately 12h 55m.
Frankfurt am Main to Brescia bus services, operated by FlixBus, depart from Frankfurt central train station.
Frankfurt am Main to Brescia bus services, operated by FlixBus, arrive at Brescia - North Bus Station.
Book your Frankfurt am Main to Brescia bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Frankfurt am Main and Brescia is 521.9 km. The road distance is 777 km.
You can take a bus from Frankfurt central train station to Brescia - North Bus Station via Milano, Autostazione Lampugnano in around 12h 20m.