The average bus between Frankfurt am Main and Ensisheim takes 8h 25m and the fastest bus takes 6h 42m. The bus service runs several times per day from Frankfurt am Main to Ensisheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Frankfurt am Main and Ensisheim. The earliest departure is at 3:50 AM at night, and the last departure from Frankfurt am Main is at 10:45 PM which arrives into Ensisheim at 7:27 AM. All services require a transfer at Karlsruhe central train station and take an average of 8h 25m. The schedules shown below are for the next available departures.
Arrives next day



9h 12m • 3 changes
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8h 42m • 3 changes



8h 37m • 3 changes



7h 10m • 3 changes
Arrives next day



11h 7m • 3 changes
Arrives next day



8h 42m • 3 changes



8h 37m • 3 changes



7h 10m • 3 changes
Arrives next day



11h 7m • 3 changes
Arrives next day



8h 42m • 3 changes
Arrives next day



11h 7m • 3 changes
Arrives next day



8h 42m • 3 changes
Want to know about travelling from Frankfurt am Main to Ensisheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Frankfurt am Main to Ensisheim. However, there are services departing from Frankfurt am Main station and arriving at Ensisheim station via Karlsruhe central train station station. The journey, including transfers, takes approximately 8h 25m.
Frankfurt am Main to Ensisheim bus services, operated by FlixBus, depart from Frankfurt central train station.
Frankfurt am Main to Ensisheim bus services, operated by FlixBus, arrive at Colmar station.
The distance between Frankfurt am Main and Ensisheim is 268.3 km. The road distance is 342 km.
You can take a bus from Frankfurt central train station to Ensisheim - Hlm via Karlsruhe central train station, Strasbourg - L'Étoile Park Bus Station, Colmar, and COLMAR - Gare SNCF in around 7h 35m.