The average bus between Frankfurt am Main and Lisse takes 8h 59m and the fastest bus takes 7h 55m. The bus service runs several times per day from Frankfurt am Main to Lisse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Frankfurt am Main and Lisse. The earliest departure is at 1:20 AM at night, and the last departure from Frankfurt am Main is at 1:20 PM which arrives into Lisse at 11:16 PM. All services require a transfer at Amsterdam Sloterdijk and take an average of 8h 59m. The schedules shown below are for the next available departures.


8h 50m • 2 changes


8h 15m • 2 changes


7h 55m • 2 changes


10h 54m • 2 changes


8h 14m • 2 changes


8h 24m • 2 changes


11h 24m • 2 changes


9h 39m • 2 changes


8h 16m • 2 changes


8h 26m • 2 changes


11h 26m • 2 changes


9h 41m • 2 changes


8h 50m • 2 changes


8h 15m • 2 changes


7h 55m • 2 changes


10h 54m • 2 changes


8h 50m • 2 changes


8h 15m • 2 changes


10h 54m • 2 changes


7h 55m • 2 changes


8h 50m • 2 changes


8h 15m • 2 changes


7h 55m • 2 changes


10h 54m • 2 changes
Want to know about travelling from Frankfurt am Main to Lisse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Frankfurt am Main to Lisse. However, there are services departing from Frankfurt am Main station and arriving at Lisse station via Amsterdam Sloterdijk. The journey, including transfers, takes approximately 8h 59m.
Frankfurt am Main to Lisse bus services, operated by FlixBus, depart from Frankfurt central train station.
Frankfurt am Main to Lisse bus services, operated by FlixBus, arrive at Amsterdam Sloterdijk station.
The distance between Frankfurt am Main and Lisse is 373.5 km. The road distance is 498 km.
FlixBus operates a bus from Frankfurt central train station to Amsterdam Sloterdijk every 2 hours. Tickets cost €35–65 and the journey takes 6h 10m. RegioJet also services this route once daily.