The bus between Frankfurt am Main and Palermo takes 45h 30m. The bus runs, on average, 6 times per week from Frankfurt am Main to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Frankfurt am Main and Palermo. The earliest departure is at 5:45 PM in the evening, and the last departure from Frankfurt am Main is at 5:45 PM which arrives into Palermo at 3:15 PM. All services require a transfer at Offenbach and take an average of 45h 30m. The schedules shown below are for the next available departures.
Want to know about travelling from Frankfurt am Main to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Frankfurt am Main to Palermo. However, there are services departing from Frankfurt am Main station and arriving at Palermo station via Palermo Piazza Cairoli. The journey, including transfers, takes approximately 45h 30m.
Frankfurt am Main to Palermo bus services, operated by FlixBus, depart from Mühlheim am Main station.
Frankfurt am Main to Palermo bus services, operated by FlixBus, arrive at Palermo Piazza Cairoli station.
Book your Frankfurt am Main to Palermo bus tickets online with FlixBus.
The distance between Frankfurt am Main and Palermo is 1,382.5 km. The road distance is 3,815 km.
Onebus operates a bus from Mühlheim am Main to Palermo Piazza Cairoli once a week, and the journey takes 28h 19m.
