Frankfurt am Main to Prague Buses

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Duration	6h 47m
Distance	509.3 km
Average price	850 Kč
Frequency	2/day

Trip overview

Bus

Frankfurt am Main

Prague

The average bus between Frankfurt am Main and Prague takes 6h 47m and the fastest bus takes 6h 15m. The bus service runs several times per day from Frankfurt am Main to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

Bus

Frankfurt Central Train Station
Prague

6h 15m

600 Kč - 1 200 Kč

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Frankfurt am Main to Prague bus times

Buses run twice daily between Frankfurt am Main and Prague. The earliest departure is at 17:05 in the afternoon, and the last departure from Frankfurt am Main is at 22:30 which arrives into Prague at 04:45. All services run direct with no transfers required, and take on average 6h 47m. The schedules shown below are for the next available departures.

Departing Tuesday, September 16, 2025

FlixBus

17:05 Frankfurt am Main

22:30 Frankfurt am Main

Departing Wednesday, September 17, 2025

FlixBus

17:05 Frankfurt am Main

22:30 Frankfurt am Main

Departing Thursday, September 18, 2025

FlixBus

17:05 Frankfurt am Main

22:30 Frankfurt am Main

Departing Friday, September 19, 2025

FlixBus

17:05 Frankfurt am Main

22:30 Frankfurt am Main

Departing Saturday, September 20, 2025

FlixBus

17:05 Frankfurt am Main

22:30 Frankfurt am Main

Frequently asked questions

Want to know about travelling from Frankfurt am Main to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport?, What is the quickest option?, How much do tickets usually cost? and many more.

Is there a direct bus between Frankfurt am Main and Prague?

Yes, there is a direct bus departing from Frankfurt Central Train Station station and arriving at Praha, Hlavní Nádraží. Services depart twice daily, and operate every day. The journey takes approximately 6h 15m.

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How far is it from Frankfurt am Main to Prague?

The distance between Frankfurt am Main and Prague is 507 km. The road distance is 509.3 km.

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Where do I catch the Frankfurt am Main to Prague bus from?

Frankfurt am Main to Prague bus services, operated by RegioJet, depart from Frankfurt Central Train Station.

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Where does the Frankfurt am Main to Prague bus arrive?

Frankfurt am Main to Prague bus services, operated by RegioJet, arrive at Praha, Hlavní Nádraží station.

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How do I get a bus ticket from Frankfurt am Main to Prague?

Book your Frankfurt am Main to Prague bus tickets online with Omio, Distribusion and FlixBus.

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Where can I stay near Prague?

There are 3942+ hotels available in Prague.

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What companies run services between Frankfurt am Main and Prague?

RegioJet operates a bus from Frankfurt Central Train Station to Praha, Hlavní Nádraží once daily. Tickets cost 600 Kč - 850 Kč and the journey takes 6h 15m. FlixBus also services this route once daily.

Bus operators

RegioJet

Ave. Duration

6h 15m

Frequency

Once daily

Estimated price

600 Kč - 850 Kč

Phone: +420 222 222 221
Email: info@regiojet.cz
Website: regiojet.com

Bus from Frankfurt Central Train Station to Praha, Hlavní Nádraží

Ave. Duration: 6h 15m
Frequency: Once daily
Estimated price: 600 Kč - 850 Kč
Website: https://regiojet.com/

FlixBus

Ave. Duration

7h 20m

Frequency

Once daily

Estimated price

600 Kč - 1 200 Kč

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).