Bus Frankfurt am Main to Strasbourg (Station) from €32 | Tickets & Timetables

Frankfurt am Main to Strasbourg (Station) buses

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Trip Overview

The average bus between Frankfurt am Main and Strasbourg (Station) takes 4h 20m and the fastest bus takes 3h 44m. There is a bus service every few hours from Frankfurt am Main to Strasbourg (Station). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 20m
Duration: 243 km
Distance: €32
Average price: Hourly
Frequency

Bus

best

Take the bus from Frankfurt central train station to Karlsruhe central train stationbus FlixBus 108 / ...
Take the bus from Karlsruhe central train station to Strasbourgbus FlixBus 108 / ...

4h 36m

€21–68

Frankfurt am Main to Strasbourg (Station) bus times

Buses run hourly between Frankfurt am Main and Strasbourg (Station). The earliest departure is at 12:40 AM at night, and the last departure from Frankfurt am Main is at 10:45 PM which arrives into Strasbourg (Station) at 5:47 AM. All services require a transfer at Karlsruhe central train station and take an average of 4h 20m. The schedules shown below are for the next available departures.

Departing Sunday, August 23, 2026

3:15 PM → 7:38 PM
4h 23m • 2 changes
5:15 PM → 8:59 PM
3h 44m • 2 changes
5:45 PM → 9:57 PM
4h 12m • 2 changes
6:00 PM → 11:57 PM
5h 57m • 2 changes
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Departing Monday, August 24, 2026

12:40 AM → 4:47 AM
4h 7m • 2 changes
3:30 AM → 9:45 AM
6h 15m • 2 changes
3:50 AM → 8:10 AM
4h 20m • 2 changes
4:35 AM → 8:58 AM
4h 23m • 2 changes
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Departing Tuesday, August 25, 2026

12:40 AM → 4:47 AM
4h 7m • 2 changes
3:30 AM → 9:45 AM
6h 15m • 2 changes
3:50 AM → 8:10 AM
4h 20m • 2 changes
4:35 AM → 8:58 AM
4h 23m • 2 changes
Show more

Departing Wednesday, August 26, 2026

12:40 AM → 4:47 AM
4h 7m • 2 changes
3:50 AM → 8:10 AM
4h 20m • 2 changes
4:35 AM → 8:58 AM
4h 23m • 2 changes
6:30 AM → 12:35 PM
6h 5m • 2 changes
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Frequently asked questions

Want to know about travelling from Frankfurt am Main to Strasbourg (Station)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Frankfurt am Main, Germany and Strasbourg (Station), Grand Est, France?

You can take a bus from Frankfurt central train station to Gare Centrale via Karlsruhe central train station, Strasbourg, and Etoile Bourse in around 4h 36m.

Operators