The average bus between Frederick and Manchester takes 19h 8m and the fastest bus takes 12h 40m. There is at least one bus per day from Frederick to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Frederick and Manchester. The earliest departure is at 11:30 AM in the morning, and the last departure from Frederick is at 7:30 PM which arrives into Manchester at 8:10 AM. All services require a transfer at Baltimore Downtown Bus Station and take an average of 19h 8m. The schedules shown below are for the next available departures.
Arrives next day



20h 40m • 3 changes
Arrives next day



18h 50m • 3 changes
Arrives next day



20h 40m • 3 changes
Arrives next day



18h 50m • 3 changes
Want to know about travelling from Frederick to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Frederick to Manchester. However, there are services departing from Frederick station and arriving at Manchester station via Baltimore Downtown Bus Terminal, Baltimore, MD. The journey, including transfers, takes approximately 19h 8m.
Frederick to Manchester bus services, operated by BayRunner Shuttle, depart from Frederick Bayrunner Office station.
Frederick to Manchester bus services, operated by BayRunner Shuttle, arrive at Manchester(Veterans Memorial Park) station.
Book your Frederick to Manchester bus tickets online with BayRunner Shuttle, Flixbus USA and Greyhound USA.
The distance between Frederick and Manchester is 637.6 km. The road distance is 885 km.
You can take a bus from Frederick Bayrunner Office to Manchester(Veterans Memorial Park) via Baltimore Downtown Bus Station, New York Midtown, and Boston in around 12h 43m.