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Frederick to Salem buses

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Trip Overview

The average bus between Frederick and Salem takes 15h 40m and the fastest bus takes 12h 19m. The bus service runs several times per day from Frederick to Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 40m
Duration
521 mi
Distance
$126
Average price
Twice daily
Frequency

Frederick to Salem bus times

Buses run twice daily between Frederick and Salem. The earliest departure is at 7:15 AM in the morning, and the last departure from Frederick is at 7:30 PM which arrives into Salem at 9:28 AM. All services require a transfer at Baltimore and take an average of 15h 40m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA24h 34m • 4 changes
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    Arrives next day

    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA13h 58m • 4 changes

Departing Wednesday, November 11, 2026

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    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA13h 14m • 4 changes
  •  → 

    Arrives next day

    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA20h 19m • 4 changes
  •  → 

    Arrives next day

    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA13h 58m • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA13h 14m • 4 changes
  •  → 

    Arrives next day

    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA20h 19m • 4 changes
  •  → 

    Arrives next day

    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA13h 58m • 4 changes

Departing Friday, November 13, 2026

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    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA13h 14m • 4 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA12h 19m • 4 changes

Departing Monday, November 16, 2026

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    BayRunner ShuttleFlixbus USAFlixbus USAMBTAMBTA13h 14m • 4 changes

Frequently asked questions

Want to know about travelling from Frederick to Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Frederick to Salem.ExpandLaunch map view
  • Distance: 521.1 mi
  • Duration: 15h 40m

What companies run services between Frederick, MD, USA and Salem, MA, USA?

You can take a bus from Frederick to Salem via Baltimore, New York, Boston, South Station, Chelsea, and Chelsea in around 12h 36m.

Operators