The average bus between Fresno and San Luis Obispo takes 15h 25m and the fastest bus takes 11h 19m. There is at least one bus per day from Fresno to San Luis Obispo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Fresno and San Luis Obispo. The earliest departure is at 4:36 PM in the afternoon, and the last departure from Fresno is at 5:53 PM which arrives into San Luis Obispo at 1:25 PM. All services require a transfer at Gilroy and take an average of 15h 25m. The schedules shown below are for the next available departures.
Arrives next day


11h 19m • 2 changes
Arrives next day


19h 32m • 2 changes
Arrives next day


11h 19m • 2 changes
Arrives next day


19h 32m • 2 changes
Arrives next day


11h 19m • 2 changes
Arrives next day


19h 32m • 2 changes
Want to know about travelling from Fresno to San Luis Obispo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Fresno to San Luis Obispo. However, there are services departing from Fresno station and arriving at San Luis Obispo station via Gilroy. The journey, including transfers, takes approximately 15h 25m.
Fresno to San Luis Obispo bus services, operated by Tufesa, depart from Fresno, CA station.
Fresno to San Luis Obispo bus services, operated by Tufesa, arrive at San Luis Obispo station.
Book your Fresno to San Luis Obispo bus tickets online with Tufesa, Monterey-Salinas Transit and Amtrak.
The distance between Fresno and San Luis Obispo is 181.4 km. The road distance is 443 km.
You can take a bus from Fresno, CA to San Luis Obispo via Gilroy, Monterey / Gilroy Train Station, and Salinas in around 8h 12m.