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Frosinone to Brindisi buses

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Trip Overview

The average bus between Frosinone and Brindisi takes 16h 4m and the fastest bus takes 12h 58m. The bus runs, on average, 6 times per week from Frosinone to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 4m
Duration
516 km
Distance
€51
Average price
6 times a week
Frequency

Frosinone to Brindisi bus times

Buses run 6 times a week between Frosinone and Brindisi. The earliest departure is at 6:00 PM in the evening, and the last departure from Frosinone is at 11:54 PM which arrives into Brindisi at 7:15 AM. All services require a transfer at Bari and take an average of 16h 4m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.FlixBusFlixBus12h 58m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.FlixBusFlixBus12h 58m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.FlixBusFlixBus13h 15m • 2 changes
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    Arrives +2 days

    Cotral S.p.A.FlixBusFlixBus31h 20m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.FlixBusFlixBus12h 58m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.FlixBusFlixBus12h 58m • 2 changes

Frequently asked questions

Want to know about travelling from Frosinone to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Frosinone to Brindisi.ExpandLaunch map view
  • Distance: 516.3 km
  • Duration: 16h 4m

What companies run services between Frosinone, Lazio, Italy and Brindisi, Italy?

You can take a bus from FROSINONE | via Vado del Tufo # f99935 to Brindisi Istituto Professionale Falcone via Frosinone, Bari, and Bari FS Park - Via Capruzzi in around 8h 47m.

Operators