The average bus between Gainesville and Downtown Orlando takes 2h 36m and the fastest bus takes 2h 12m. The bus service runs several times per day from Gainesville to Downtown Orlando. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Gainesville and Downtown Orlando. The earliest departure is at 2:40 AM at night, and the last departure from Gainesville is at 6:30 PM which arrives into Downtown Orlando at 9:10 PM. All services require a transfer at Orlando Bus Station and take an average of 2h 36m. The schedules shown below are for the next available departures.

2h 50m • 1 change

3h 16m • 1 change

2h 32m • 1 change

3h 1m • 1 change

2h 32m • 1 change

3h 1m • 1 change

2h 32m • 1 change

3h 1m • 1 change

2h 32m • 1 change

3h 1m • 1 change

2h 32m • 1 change

3h 1m • 1 change
Want to know about travelling from Gainesville to Downtown Orlando? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Gainesville to Downtown Orlando. However, there are services departing from Gainesville station and arriving at Downtown Orlando station via Orlando Bus Station station. The journey, including transfers, takes approximately 2h 36m.
Gainesville to Downtown Orlando bus services, operated by Flixbus USA, depart from Gainesville station.
Gainesville to Downtown Orlando bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
The distance between Gainesville and Downtown Orlando is 154.8 km. The road distance is 181 km.
FlixBus-us operates a bus from Gainesville to Orlando Bus Station every 4 hours, and the journey takes 1h 55m. Flixbus USA also services this route 5 times a day.